It is found that the anthrax toxin works to alter signaling in pain-sensing neurons and, when delivered in a targeted manner into neurons of the central and peripheral nervous system, can offer relief to animals in distress.
The technique may soon help design novel precision-targeted pain treatments without the widespread systemic effects.
“This molecular platform of using a bacterial toxin to deliver substances into neurons and modulate their function represents a new way to target pain-mediating neurons,” says study senior investigator Isaac Chiu, associate professor of immunology in the Blavatnik Institute at Harvard Medical School.
Source: Medindia
