Pregnant women with excessive gestational weight gain were more likely to be at risk of developing cardiovascular risk later in life, reveals a new study published in the peer-reviewed Journal of Women’s Health.
Franya Hutchins, Ph.D., from the University of Pittsburgh Graduate School of Public Health, and coauthors used two main measures to determine a woman’s cardiovascular disease risk: the atherosclerotic cardiovascular disease (ASCVD) risk score and a measure of the C-reactive protein (CRP), an inflammatory biomarker.
‘Pregnant women who have a history of excessive gestational weight gain were at higher atherosclerotic cardiovascular disease (ASCVD) risk.’
The investigators measured these variables at baseline and at 10 follow-up visits, for a total of 20 years of follow-up.
Having a history of excessive gestational weight gain was associated with a 29.6% higher ASCVD risk score at baseline.
“In the model including confounders and midlife abdominal obesity, excessive gestational weight gain remained associated with a 9.1% higher ASCVD score,” stated the investigators.
Excessive gestational weight gain was associated with an 89.2% higher baseline CRP level. With the addition of cofounders and midlife abdominal obesity, excessive gestational weight gain remained associated with a 31.5% higher mean CRP.
“In this group of women, a history of excessive gestational weight gain was associated with a small but statistically significant higher ASCVD score and a moderate, statistically significant higher mean CRP level into midlife,” says Journal of Women’s Health Editor-in-Chief Susan G. Kornstein, MD, Executive Director of the Virginia Commonwealth University Institute for Women’s Health, Richmond, VA.
Source: Eurekalert
