The study included 1363 patients for whom D-dimer was quantitatively assessed within 24 hours of suspected or confirmed snakebite.
Diagnostic performance of D-Dimer Test
D-dimer values increased to 2.5 mg/L in three hours of the bite among 95% of patients who developed VICC, and were lower than 2.5 mg/L for 95% of non-envenomed patients up to six hours
after snakebite.
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Diagnostic performance enhanced during the first three hours after snakebite; for quantitative D-dimer testing at 2-6 hours.
One of 84 patients who developed VICC-related acute kidney injury, D-dimer values
exceeded 4 mg/L within 24 hours of the bite.
The study concluded that D-dimer concentrations estimated 2-6 hours after snakebite, with a cut-off value of 2.5 mg/L, could serve as a vital diagnostic tool for detecting VICC.
Source: Medindia
