A recent study, featured in The Lancet, sheds light on previously unseen insights into the significantly high mortality rates caused by the COVID-19 pandemic worldwide. Countries like Mexico City, Peru, and Bolivia witnessed substantial declines in life expectancy from 2019 to 2021.

This research, presenting updated estimates from the Global Burden of Disease Study (GBD) 2021, offers the most comprehensive analysis of the pandemic’s impact on human health to date, revealing a global life expectancy reduction of 1.6 years from 2019 to 2021, marking a stark departure from previous increases. Notably, amidst the pandemic, child mortality rates continued their decline, with half a million fewer deaths among children under 5 in 2021 compared to 2019. Mortality rates among children under 5 decreased by 7% from 2019 to 2021, according to GBD’s key findings.

“For adults worldwide, the COVID-19 pandemic has had a more profound impact than any event seen in half a century, including conflicts and natural disasters,” says co-first author Dr. Austin E. Schumacher, Acting Assistant Professor of Health Metrics Sciences at the Institute for Health Metrics and Evaluation (IHME) at the University of Washington. “Life expectancy declined in 84% of countries and territories during this pandemic, demonstrating the devastating potential impacts of novel pathogens.”

Researchers from IHME identified high mortality during the COVID-19 pandemic in places that were previously less recognized and/or reported. In analyzing subnational locations not previously investigated, the South African provinces of KwaZulu-Natal and Limpopo had among the highest age-adjusted excess mortality rates and largest life expectancy declines during the pandemic in the world. Conversely, the places with some of the lowest age-adjusted excess mortality from the pandemic during this period included Barbados, New Zealand, and Antigua and Barbuda.

Did You Know?

Jordan and Nicaragua experienced significant excess mortality attributable to the COVID-19 pandemic, a trend not previously captured in overall excess mortality estimates.

During the COVID-19 pandemic, mortality among older people worldwide rose in ways unseen in the previous 70 years. While the pandemic was devastating, killing approximately 16 million people around the globe in 2020 and 2021 combined, it did not completely erase historic progress – life expectancy at birth rose by nearly 23 years between 1950 and 2021.

GBD 2021 analyzes past and current demographic trends at global, regional, national, and subnational levels. The study provides globally comparable measures of excess mortality and is one of the first studies to fully evaluate demographic trends in the context of the first two years of the COVID-19 pandemic. In estimating excess deaths due to the pandemic, the authors accounted for deaths from the virus that causes COVID-19, SARS-CoV-2, as well as deaths associated with indirect effects of the pandemic, such as delays in seeking health care.

GBD 2021 goes beyond assessing the impact of the first two years of the COVID-19 pandemic. As the authors note, it also offers “implications for the future of health-care systems, economies, and societies and … a valuable foundation for policy evaluation, development, and implementation around the world.”

GBD 2021 indicates that, despite early warnings that COVID-19 could threaten the gains that the world had made in saving children’s lives, these improvements continued during the pandemic, albeit at a slower pace. Still, stark differences in child mortality persist between regions. In 2021, one out of every four children who died worldwide lived in South Asia, while two out of every four children who died lived in sub-Saharan Africa.

“Our study suggests that, even after taking stock of the terrible loss of lives the world experienced due to the pandemic, we have made incredible progress over 72 years since 1950, with child mortality continuing to drop globally,” said co-first author Dr. Hmwe Hmwe Kyu, Associate Professor of Health Metrics Sciences at IHME at the University of Washington. “Now, continuing to build on our successes, while preparing for the next pandemic and addressing the vast disparities in health across countries, should be our greatest focuses.”

The GBD 2021 study also assessed population trends. Beginning in 2017, the rate of global population growth began to drop following years of stagnation. Then, during the COVID-19 pandemic, these declines accelerated. As of 2021, 56 countries have reached peak population. Now, these countries are seeing their populations shrink. However, rapid population growth has continued in many lower-income countries. In addition, populations around the world are aging. Between 2000 and 2021, the number of people who were 65 and older grew faster than the number of people under age 15 in 188 countries and territories.

“Slowing population growth and aging populations, along with the concentration of future population growth shifting to poorer locations with worse health outcomes, will bring about unprecedented social, economic, and political challenges, such as labor shortages in areas where younger populations are shrinking and resource scarcity in places where population size continues to expand rapidly,” says Dr. Schumacher. “This is worth restating, as these issues will require significant policy forethought to address in the affected regions. As one example, nations around the world will need to cooperate on voluntary emigration, for which one source of useful guidance is the UN’s Global Compact for Safe, Orderly and Regular Migration.”

Source-Eurekalert