Using electronic health record (EHR) data of 15,215,178 persons aged over 5 years from 40 US health care systems during January 1, 2021-January 31, 2022, the investigators calculated incidences of all these cardiac outcomes among all persons.
The results showed that the incidence of cardiac outcomes after mRNA Covid-19 vaccination was highest for boys aged 12-17 years after the second vaccine dose.
However, within this demographic group, the risk for cardiac outcomes was 1.8-5.6 times as high after SARS-CoV-2 infection than after the second vaccine dose.
Further, the risk for cardiac outcomes was likewise significantly higher – about 2 to 115 times – after SARS-CoV-2 infection than after first, second, or unspecified dose of mRNA Covid-19 vaccination for all other groups by sex and age.
“Analysis of EHR data from 40 US health care systems found that the incidences of cardiac complications after SARS-CoV-2 infection or mRNA Covid-19 vaccination were low overall but were higher after infection than after vaccination for both males and females in all age groups,” said corresponding author Jason P. Block, Department of Population Medicine, from Harvard Medical School, US.
The team also cited two studies from Israel and the UK that showed similar higher risk for myocarditis after SARS-CoV-2 infection compared with that after mRNA Covid-19 vaccination.
Source: IANS
