The new research team led by Xianhui Qin, MD from Nanfang Hospital, Southern Medical University, in China demonstrates how come individuals with no previous history of kidney disease but experience
. The findings of this study are published in the
.
‘Individuals who had persistent depressive symptoms showed 1.4 times increased risk of rapid kidney function decline than those who had infrequent depressive symptoms.’
“CKD is a leading risk factor for cardiovascular disease, kidney failure, and mortality worldwide. Therefore, the identification of more modifiable risk factors may possibly reduce the huge burden of CKD and its related complications by leading to early detection and prevention,” said Dr. Qin.
Depressed people at the risk of kidney disease
The research team examined 4,763 individuals with healthy kidneys who were enrolled in the China Health and Retirement Longitudinal Study (CHARLS). The percentage of people with depressive symptoms was 39% and after a median follow-up of 4 years, rapid kidney function decline was encountered in 260 participants, who constitute about 6% of the total.
When adjustments were made for some confounding factors, it was found that individuals who had persistent depressive symptoms showed 1.4 times increased risk of rapid kidney function decline than those who had infrequent depressive symptoms .
“While our study does not show causality, it demonstrated that high depressive symptoms were significantly associated with rapid decline in kidney function among Chinese adults with normal kidney function. If further confirmed, our data provide some evidence for depressive symptom screening and effective psychosocial interventions to improve the prevention of CKD,” Qin concluded.
Source: Medindia
