I am often faced with patients in my cardiology practice who have a coronary history and most also have arthritic and orthopedic pains prompting them to take NSAIDS.
Although these medications can provide relief from pain temporarily, as a class they increase patients risks for strokes and heart attacks and I inevitably recommend minimization of NSAIDS but for those with mild to moderate pain I strongly recommend CBD oil in its various forms. These are great anti-inflammatory meds that do not increase the risk for cardiovascular events the way Celebrex, Aleve, Naprosyn, ibuprofen or Advil can with chronic use. This is the point where the patient turns to their partner and jokes about getting a prescription for marijuana.
This is why I wanted to post today to explain the Endocannabinoid system and CBD.
What is the Endocannabinoid system and how does it work?
The endocannabinoid system or ECS is a body wide signaling network that promotes homeostasis. In other words as your external environment changes the ECS keeps your body’s internal processes stable. When life stresses increase for example, the ECS helps maintain neuroplasticity to reduce the risk of depression and anxiety. In a similar way, the ECS helps balance processes that resolve inflammation and regulate immune response.
So, how does it work?
The ECS is a network of receptors and signaling molecules. The two types of receptors are called CB1 and CB2. As threats to your biological balance arise, signaling molecules called endocannabinoids or ECBs bind to CB1 And CB2 receptors triggering a cascade of signals that help maintain homeostasis. Our bodies naturally produce ECBs but poor diet and lack of exercise and other factors can disrupt ECB production. This contributes to biological imbalance and conditions such as chronic inflammation, poor immune response, depression and anxiety.
CB2 receptors are present on cells throughout the immune system and are involved in resolving inflammation. Your immune system often triggers inflammation throughout the body. In response to this inflammation, the endocannabinoid system or ECS releases endocannabinoids or ECBs called Anandamide or 2-AG. When Anandamide or 2-AG binds to immune system CB2 receptors they help initiate the resolution phase of inflammation. An effective endocannabinoid system is therefore like a dance partner working with your immune system to create a balanced interplay of healthy inflammation and resolution.
Poor diet, lack of exercise, and other factors can disrupt your body’s natural ability to produce Anandamide and 2-AG. This effectively ruins this important dance and contributes to unresolved chronic inflammation.
The good news is that hemp oil and omega 3 fatty acids will help restore an impaired ECS. Hemp oil which contains less than 0.3% or less of THC is a food grade oil with natural cannabinoids and Phyto actives that bind to CB2 receptors. Omega 3 fatty acids help your body to create more of its own endocannabinoids, Anandamide and 2-AG. Taken together, Hemp oil and omega 3’s help restore your ECS so that it can work with your own immune system to effectively resolve inflammation.
So for those with mild to moderate pain, poor diet, and a sedentary lifestyle, Hemp oil or CBD and omega 3 fatty acids are excellent supplements to help improve their sense of well-being. Being able to achieve optimal health and reduce medications is what WPR Medical strives to do.
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