Scientists find lean subjects made protective antibodies after infection while obese subjects did not make protective antibodies—they made maladaptive autoantibodies instead. Researchers speculate that leptin plays a role in skewing the immune response toward autoimmunity after infection.

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—————————————–Show Notes————————————–

0:00 Intro
0:09 Endemic Virus
0:59 Obese Don’t Make Protective Antibodies
1:15 Obese people make autoantibodies
1:40 Leptin and Fat on Fire
2:40 Leptin exacerbates inflammation, autoimmunity
3:13 Study we’re discussing
3:49 Make Americans Healthy Again
4:35 Blood Work MasterClass
5:30 Daniela Frasca, PhD: Obesity Hinders Immune System Response
6:10 Antibodies and BMI, C-Reactive Protein
6:43 Metainflammation and Inflammaging
7:15 Blood sugar and inflammation
8:13 Leptin and immunity
9:29 Summary of Study: immune tolerance breakdown
11:30 Lifestyle matters
12:30 Antibodies directed at fat tissue
12:52 Omega-6 Oils, Seed Oils & autoimmunity
13:50 Excess deaths related to heart disease on the rise
14:42 Image: CRP and autoantibodies
15:39 New study summary
16:21 Italy Research from fat cell spill over
16:58 Obesity is an autoimmune disease
17:05 Change your habits
17:47 Image: Behavior model
Book: https://amzn.to/3CbpvEQ

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