Volunteers who enrolled in the study provided researchers with three separate blood draws. Samples were collected before the vaccine rollout and during the Delta and Omicron variants. To date, investigators have completed three different phases of the study.
“This is the first study from the Texas CARES survey that includes data from all three time points in the survey,” said Sarah Messiah, PhD, MPH, corresponding author of the study and professor of epidemiology, human genetics, and environmental sciences at UTHealth School of Public Health Dallas campus. “These findings are important because the information we collected from children infected with COVID-19 didn’t differ at all by whether a child was asymptomatic, severity of symptoms, when they had the virus, were at a healthy weight or had obesity, or by gender. It was the same for everyone.”
The results of Texas CARES, Messiah said, are just a step in understanding the virus’s impact on children. To date, 14 million kids in the U.S. have tested positive for the virus, she said.
“Adult literature shows us that natural infection, plus the vaccine-induced protection, gives you the best defense against COVID-19. There has been a misunderstanding from some parents who think just because their child has had COVID-19, they are now protected and don’t need to get the vaccine. While our study is encouraging in that some amount natural antibodies last at least six months in children, we still don’t know the absolute protection threshold. We have a great tool available to give children additional protection by getting their vaccine, so if your child is eligible, take advantage of it,” Messiah said.
The Texas CARES study is ongoing. To learn more about how to get involved visit https://sph.uth.edu/projects/texascares/.
Additional UTHealth Houston authors included Stacia DeSantis, PhD; Luis Leon-Novelo, PhD; Yashar Talebi, MS; Frances Brito, MSc; Harold W. Kohl, III, PhD, MS; Melissa Valerio-Shewmaker, PhD; Jessica Ross, BS; Michael D. Swartz, PhD; Ashraf Yaseen, PhD; Steven H. Kelder, PhD, MPH; Shiming Zhang, MS; Onyinye S. Omega-Njemnobi, MD, PhD; Michael O. Gonzalez, MPH; Leqing Wu, MS; and Eric Boerwinkle, PhD. Other authors included David Lakey, MD, with The University of Texas System; and Jennifer A. Shuford, MD, MPH and Stephen J. Pont, MD, MPH, with the Texas Department of State Health Services.
The study was funded and supported by the Texas Department of State Health Services (#HHS000866600001) and the University of Texas System.
Source: Eurekalert