Vaccination and Counter Measures Against Monkeypox


Experts believe vaccination after a monkeypox exposure may help prevent or cause the disease to become less severe.

Persons exposed to the monkeypox virus and who have not received the smallpox vaccine within the last three years should consider getting vaccinated.

The sooner an exposed individual gets the vaccine, the better. CDC recommends providing vaccine within four days from the date of exposure. Given during 4 to 14 days, vaccination may decrease the symptoms of the disease but may not prevent the disease.

Available Medical Countermeasures for Monkeypox

Currently, there is no approved specific treatment for monkeypox. But antivirals developed for smallpox may provide some benefits (3✔ ✔Trusted Source
Interim Clinical Guidance for the Treatment of Monkeypox

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).

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The following counter measures are currently available from the Strategic National Stockpile (SNS):

Brincidofovir has an improved safety profile over Cidofovir. Although human studies are lacking, Cidofovir and Brincidofovir have proven activity against poxviruses in in-vitro and animal studies.

References :

  1. Monkeypox – (https://www.who.int/news-room/fact-sheets/detail/monkeypox)

  2. Treatment – (https://www.cdc.gov/poxvirus/monkeypox/treatment.html)

  3. Interim Clinical Guidance for the Treatment of Monkeypox – (https://www.cdc.gov/poxvirus/monkeypox/clinicians/treatment.html#:~:text=At%20this%20time%2C%20there%20are,to%20control%20a%20monkeypox%20outbreak)

  4. Highlights of Prescribing Information – (https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/208627s000lbl.pdf)

Source: Medindia



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