“This work provides a new understanding of how products affect the physical properties of our skin, which includes not just skin health, but also skin sensorial perception. That’s a significant advance,” said Reinhold Dauskardt, Professor in Stanford’s Department of Materials Science and Engineering.

Cleansing Affects Your Stratum Corneum

The team predicted that the mechanical forces created by this shrinking or swelling propagate through the skin to reach mechanoreceptors (a sense organ) below the epidermis, which then fire off signals to the brain that we interpret as a feeling of skin tightness.

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In the study, researchers studied the effects of nine different moisturizing formulas and six different cleansers on donor skin samples from three locations on the human body — cheek, forehead, and abdomen.

They measured changes in the stratum corneum in the lab and then fed that information into a sophisticated model of human skin to predict the signals that the mechanoreceptors would send.

The predictions from their analysis lined up almost perfectly with what people reported in human trials for each formula. Collaborators at L’Oral Research and Innovation recruited 2,000 women in France to assess the nine moisturizers and 700 women in China to assess the six cleansers.

The participants ranked their perceived feelings of skin tightness after using the formula they were given.

“The ability to understand and predict how people will feel after using a skin treatment could help cosmetics companies improve their formulations before bringing in people to test them,” said Dauskardt.

“What we’ve done is reveal how mechanical information gets from the outer stratum corneum layer down to the neurons much lower in the skin layers,” Dauskardt noted.

Source: IANS