there was minimal overlap between the protein profiles of baseline VO2max and its response to the exercise training intervention helped the research team to develop a protein score to improve their ability to predict an individual’s trainability, or change in VO2max.

“We now have a detailed list of new blood compounds that further inform our understanding of the biology of fitness and exercise adaptation, and predict individual responses to a given exercise regimen,” said Gerszten, who is also the Director of the Program in Personal Genomics and Cardiometabolic Disease at BIDMC.

In another separate community-based study the scientists discover some of these proteins were linked to an elevated risk of early death, highlighting the link between cardiorespiratory fitness and long-term health outcomes.

All these findings can help in future to explore potential interventions and provides an important step in individualizing exercise as a therapy.

Source: Medindia